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A new TROP2-targeting antibody-drug conjugate shows potent antitumor efficacy in breast and lung cancers - npj Precision Oncology

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A new TROP2-targeting antibody-drug conjugate shows potent antitumor efficacy in breast and lung cancers - npj Precision Oncology

Trophoblast cell surface antigen 2 (Trop2) is considered to be an attractive therapeutic target in cancer treatments. We previously generated a new humanized anti-Trop2 antibody named hIMB1636, and designated it as an ideal targeting carrier for cancer therapy. Lidamycin (LDM) is a new antitumor antibiotic, containing an active enediyne chromophore (AE) and a noncovalently bound apoprotein (LDP).

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A new TROP2-targeting antibody-drug conjugate shows potent antitumor efficacy in breast and lung cancers - npj Precision Oncology

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A new TROP2-targeting antibody-drug conjugate shows potent antitumor efficacy in breast and lung cancers - npj Precision Oncology

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