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OTUB1/NDUFS2 axis promotes pancreatic tumorigenesis through protecting against mitochondrial cell death - Cell Death Discovery

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OTUB1/NDUFS2 axis promotes pancreatic tumorigenesis through protecting against mitochondrial cell death - Cell Death Discovery

Pancreatic cancer is one of the most fatal cancers in the world. A growing number of studies have begun to demonstrate that mitochondria play a key role in tumorigenesis. Our previous study reveals that NDUFS2 (NADH: ubiquinone oxidoreductase core subunit S2), a core subunit of the mitochondrial respiratory chain complex I, is upregulated in Pancreatic adenocarcinoma (PAAD). However, its role in the development of PAAD remains unknown.

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OTUB1/NDUFS2 axis promotes pancreatic tumorigenesis through protecting against mitochondrial cell death - Cell Death Discovery

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OTUB1/NDUFS2 axis promotes pancreatic tumorigenesis through protecting against mitochondrial cell death - Cell Death Discovery

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