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13 days ago

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Systematic analysis of muscle aging using joint single-cell and single-nucleus sequencing - Nature Aging

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Systematic analysis of muscle aging using joint single-cell and single-nucleus sequencing - Nature Aging

Skeletal muscle is a highly heterogenous tissue that comprises multiple cell types. Leveraging single-cell and single-nucleus experiments, we systematically mapped the cellular and molecular changes across different skeletal muscle compartments with age. We identify neuromuscular-junction accessory nuclei that may be pivotal in mitigating denervation and uncovered differences between myofiber and myonucleus aging.

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Systematic analysis of muscle aging using joint single-cell and single-nucleus sequencing - Nature Aging

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Systematic analysis of muscle aging using joint single-cell and single-nucleus sequencing - Nature Aging

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