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Designer peptide–DNA cytoskeletons regulate the function of synthetic cells - Nature Chemistry

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Designer peptide–DNA cytoskeletons regulate the function of synthetic cells - Nature Chemistry

The bottom-up engineering of artificial cells requires a reconfigurable cytoskeleton that can organize at distinct locations and dynamically modulate its structural and mechanical properties. Here, inspired by the vast array of actin-binding proteins and their ability to reversibly crosslink or bundle filaments, we have designed a library of peptide–DNA crosslinkers varying in length, valency and geometry.

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Designer peptide–DNA cytoskeletons regulate the function of synthetic cells - Nature Chemistry

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Designer peptide–DNA cytoskeletons regulate the function of synthetic cells - Nature Chemistry

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