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Fatty acyl-coenzyme A activates mitochondrial division through oligomerization of MiD49 and MiD51 - Nature Cell Biology

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Fatty acyl-coenzyme A activates mitochondrial division through oligomerization of MiD49 and MiD51 - Nature Cell Biology

Mitochondrial fission occurs in many cellular processes, but the regulation of fission is poorly understood. We show that long-chain acyl-coenzyme A (LCACA) activates two related mitochondrial fission proteins, MiD49 and MiD51, by inducing their oligomerization, which activates their ability to stimulate the DRP1 GTPase.

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Fatty acyl-coenzyme A activates mitochondrial division through oligomerization of MiD49 and MiD51 - Nature Cell Biology

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Fatty acyl-coenzyme A activates mitochondrial division through oligomerization of MiD49 and MiD51 - Nature Cell Biology

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