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22 days ago

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Inflammation and mitophagy are mitochondrial checkpoints to aging - Nature Communications

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Inflammation and mitophagy are mitochondrial checkpoints to aging - Nature Communications

Cellular and organismal aging have been consistently associated with mitochondrial dysfunction and inflammation. Accumulating evidence indicates that aging-related inflammatory responses are mechanistically linked to compromised mitochondrial integrity coupled with mtDNA-driven CGAS activation, a process that is tonically inhibited by mitophagy. Cellular and organismal aging have been consistently associated with mitochondrial dysfunction and inflammation.

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Inflammation and mitophagy are mitochondrial checkpoints to aging - Nature Communications

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Inflammation and mitophagy are mitochondrial checkpoints to aging - Nature Communications

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