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22 days ago

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Identification of senescent, TREM2-expressing microglia in aging and Alzheimer's disease model mouse brain - Nature Neuroscience

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Identification of senescent, TREM2-expressing microglia in aging and Alzheimer's disease model mouse brain - Nature Neuroscience

Alzheimer's disease (AD) and dementia in general are age-related diseases with multiple contributing factors, including brain inflammation. Microglia, and specifically those expressing the AD risk gene TREM2, are considered important players in AD, but their exact contribution to pathology remains unclear.

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Identification of senescent, TREM2-expressing microglia in aging and Alzheimer's disease model mouse brain - Nature Neuroscience

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Identification of senescent, TREM2-expressing microglia in aging and Alzheimer's disease model mouse brain - Nature Neuroscience

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