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Zyxin is important for the stability and function of podocytes, especially during mechanical stretch - Communications Biology

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Zyxin is important for the stability and function of podocytes, especially during mechanical stretch - Communications Biology

Podocyte detachment due to mechanical stress is a common issue in hypertension-induced kidney disease. This study highlights the role of zyxin for podocyte stability and function. We have found that zyxin is significantly up-regulated in podocytes after mechanical stretch and relocalizes from focal adhesions to actin filaments.

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Zyxin is important for the stability and function of podocytes, especially during mechanical stretch - Communications Biology

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Zyxin is important for the stability and function of podocytes, especially during mechanical stretch - Communications Biology

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