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An in vitro CRISPR screen of cell-free DNA identifies apoptosis as the primary mediator of cell-free DNA release - Communications Biology

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An in vitro CRISPR screen of cell-free DNA identifies apoptosis as the primary mediator of cell-free DNA release - Communications Biology

Clinical circulating cell-free DNA (cfDNA) testing is now routine, however test accuracy remains limited. By understanding the life-cycle of cfDNA, we might identify opportunities to increase test performance. Here, we profile cfDNA release across a 24-cell line panel and utilize a cell-free CRISPR screen (cfCRISPR) to identify mediators of cfDNA release.

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An in vitro CRISPR screen of cell-free DNA identifies apoptosis as the primary mediator of cell-free DNA release - Communications Biology

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An in vitro CRISPR screen of cell-free DNA identifies apoptosis as the primary mediator of cell-free DNA release - Communications Biology

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Unlocking the Power of Knowledge
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Unlocking the Power of Knowledge
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