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Circulating tumor cells shielded with extracellular vesicle-derived CD45 evade T cell attack to enable metastasis - Signal Transduction and Targeted Therapy

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Circulating tumor cells shielded with extracellular vesicle-derived CD45 evade T cell attack to enable metastasis - Signal Transduction and Targeted Therapy

Circulating tumor cells (CTCs) are precursors of distant metastasis in a subset of cancer patients. A better understanding of CTCs heterogeneity and how these CTCs survive during hematogenous dissemination could lay the foundation for therapeutic prevention of cancer metastasis. It remains elusive how CTCs evade immune surveillance and elimination by immune cells.

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Circulating tumor cells shielded with extracellular vesicle-derived CD45 evade T cell attack to enable metastasis - Signal Transduction and Targeted Therapy

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Circulating tumor cells shielded with extracellular vesicle-derived CD45 evade T cell attack to enable metastasis - Signal Transduction and Targeted Therapy

Rate This Post

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Unlocking the Power of Knowledge
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Unlocking the Power of Knowledge
for Humanity's Progress