Article
Compensatory growth and recovery of cartilage cytoarchitecture after transient cell death in fetal mouse limbs - Nature Communications
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A major question in developmental and regenerative biology is how organ size and architecture are controlled by progenitor cells. While limb bones exhibit catch-up growth (recovery of a normal growth trajectory after transient developmental perturbation), it is unclear how this emerges from the behaviour of chondroprogenitors, the cells sustaining the cartilage anlagen that are progressively replaced by bone.
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