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Investigating the aspect of asymmetry in brain-first versus body-first Parkinson's disease - npj Parkinson's Disease

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Investigating the aspect of asymmetry in brain-first versus body-first Parkinson's disease - npj Parkinson's Disease

Parkinson's disease (PD) is characterized by a progressive loss of dopaminergic neurons in the substantia nigra. Recent literature has proposed two subgroups of PD. The “body-first subtype” is associated with a prodrome of isolated REM-sleep Behavior Disorder (iRBD) and a relatively symmetric brain degeneration. The “brain-first subtype” is suggested to have a more asymmetric degeneration and a prodromal stage without RBD.

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Investigating the aspect of asymmetry in brain-first versus body-first Parkinson's disease - npj Parkinson's Disease

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Investigating the aspect of asymmetry in brain-first versus body-first Parkinson's disease - npj Parkinson's Disease

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