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Radiotherapy activates picolinium prodrugs in tumours - Nature Chemistry

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Radiotherapy activates picolinium prodrugs in tumours - Nature Chemistry

Radiotherapy-induced prodrug activation provides an ideal solution to reduce the systemic toxicity of chemotherapy in cancer therapy, but the scope of the radiation-activated protecting groups is limited. Here we present that the well-established photoinduced electron transfer chemistry may pave the way for developing versatile radiation-removable protecting groups.

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Radiotherapy activates picolinium prodrugs in tumours - Nature Chemistry

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Radiotherapy activates picolinium prodrugs in tumours - Nature Chemistry

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