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Liprin-α proteins are master regulators of human presynapse assembly - Nature Neuroscience

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Liprin-α proteins are master regulators of human presynapse assembly - Nature Neuroscience

The formation of mammalian synapses entails the precise alignment of presynaptic release sites with postsynaptic receptors but how nascent cell–cell contacts translate into assembly of presynaptic specializations remains unclear. Guided by pioneering work in invertebrates, we hypothesized that in mammalian synapses, liprin-α proteins directly link trans-synaptic initial contacts to downstream steps.

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Liprin-α proteins are master regulators of human presynapse assembly - Nature Neuroscience

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Liprin-α proteins are master regulators of human presynapse assembly - Nature Neuroscience

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