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Dopamine receptor D2 confers colonization resistance via microbial metabolites - Nature

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Dopamine receptor D2 confers colonization resistance via microbial metabolites - Nature

The gut microbiome has major roles in modulating host physiology. One such function is colonization resistance, or the ability of the microbial collective to protect the host against enteric pathogens1–3, including enterohaemorrhagic Escherichia coli (EHEC) serotype O157:H7, an attaching and effacing (AE) food-borne pathogen that causes severe gastroenteritis, enterocolitis, bloody diarrhea and acute renal failure4,5 (haemolytic uremic syndrome).

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Dopamine receptor D2 confers colonization resistance via microbial metabolites - Nature

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Dopamine receptor D2 confers colonization resistance via microbial metabolites - Nature

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