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Evolutionary trajectories of small cell lung cancer under therapy - Nature

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Evolutionary trajectories of small cell lung cancer under therapy - Nature

The evolutionary processes that underlie the marked sensitivity of small cell lung cancer (SCLC) to chemotherapy and rapid relapse are unknown1–3. Here we determined tumour phylogenies at diagnosis and throughout chemotherapy and immunotherapy by multiregion sequencing of 160 tumours from 65 patients.

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Evolutionary trajectories of small cell lung cancer under therapy - Nature

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Evolutionary trajectories of small cell lung cancer under therapy - Nature

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