Article
Universal STING mimic boosts antitumour immunity via preferential activation of tumour control signalling pathways - Nature Nanotechnology
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The efficacy of STING (stimulator of interferon genes) agonists is due to various factors, primarily inefficient intracellular delivery, low/lack of endogenous STING expression in many tumours, and a complex balance between tumour control and progression. Here we report a universal STING mimic (uniSTING) based on a polymeric architecture.
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