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A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models - Nature Biotechnology

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A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models - Nature Biotechnology

Idiopathic pulmonary fibrosis (IPF) is an aggressive interstitial lung disease with a high mortality rate. Putative drug targets in IPF have failed to translate into effective therapies at the clinical level. We identify TRAF2- and NCK-interacting kinase (TNIK) as an anti-fibrotic target using a predictive artificial intelligence (AI) approach.

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A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models - Nature Biotechnology

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A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models - Nature Biotechnology

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