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Imbalanced single-cell data integration leads to loss of biological information - Nature Biotechnology

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Imbalanced single-cell data integration leads to loss of biological information - Nature Biotechnology

The Iniquitate pipeline assessed the impacts of cell-type imbalance on single-cell RNA sequencing integration through perturbations to dataset balance. The results indicated that cell-type imbalance not only leads to loss of biological signal in the integrated space, but also can change the interpretation of downstream analyses after integration.

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Imbalanced single-cell data integration leads to loss of biological information - Nature Biotechnology

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Imbalanced single-cell data integration leads to loss of biological information - Nature Biotechnology

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