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Targeting HDAC6 to treat heart failure with preserved ejection fraction in mice - Nature Communications

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$Targeting HDAC6 to treat heart failure with preserved ejection fraction in mice - Nature Communications$

Heart failure with preserved ejection fraction (HFpEF) poses therapeutic challenges due to the limited treatment options. Building upon our previous research that demonstrates the efficacy of histone deacetylase 6 (HDAC6) inhibition in a genetic cardiomyopathy model, we investigate HDAC6's role in HFpEF due to their shared mechanisms of inflammation and metabolism.

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Targeting HDAC6 to treat heart failure with preserved ejection fraction in mice - Nature Communications

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Targeting HDAC6 to treat heart failure with preserved ejection fraction in mice - Nature Communications

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