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Single-cell guided prenatal derivation of primary fetal epithelial organoids from human amniotic and tracheal fluids - Nature Medicine

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Single-cell guided prenatal derivation of primary fetal epithelial organoids from human amniotic and tracheal fluids - Nature Medicine

Isolation of tissue-specific fetal stem cells and derivation of primary organoids is limited to samples obtained from termination of pregnancies, hampering prenatal investigation of fetal development and congenital diseases. Therefore, new patient-specific in vitro models are needed. To this aim, isolation and expansion of fetal stem cells during pregnancy, without the need for tissue samples or reprogramming, would be advantageous.

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Single-cell guided prenatal derivation of primary fetal epithelial organoids from human amniotic and tracheal fluids - Nature Medicine

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Single-cell guided prenatal derivation of primary fetal epithelial organoids from human amniotic and tracheal fluids - Nature Medicine

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