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Regulation of developmental gatekeeping and cell fate transition by the calpain protease DEK1 in Physcomitrium patens - Communications Biology
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Calpains are cysteine proteases that control cell fate transitions whose loss of function causes severe, pleiotropic phenotypes in eukaryotes. Although mainly considered as modulatory proteases, human calpain targets are directed to the N-end rule degradation pathway. Several such targets are transcription factors, hinting at a gene-regulatory role.
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