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Recombinant IGF-1/BP3 protects against intestinal injury in a neonatal mouse NEC model - Pediatric Research

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Recombinant IGF-1/BP3 protects against intestinal injury in a neonatal mouse NEC model - Pediatric Research

Recombinant human IGF-1/binding protein-3 (rhIGF-1/BP3) is currently being tested in phase II clinical trials in premature infants to prevent bronchopulmonary dysplasia, but its impact on the neonatal intestine remains unclear. The aim of this study was to determine whether rhIGF-1/BP3 protects against necrotizing enterocolitis (NEC) in mice and to investigate the mechanisms involved.

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Recombinant IGF-1/BP3 protects against intestinal injury in a neonatal mouse NEC model - Pediatric Research

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Recombinant IGF-1/BP3 protects against intestinal injury in a neonatal mouse NEC model - Pediatric Research

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