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TFvelo: gene regulation inspired RNA velocity estimation - Nature Communications

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TFvelo: gene regulation inspired RNA velocity estimation - Nature Communications

RNA velocity is closely related with cell fate and is an important indicator for the prediction of cell states with elegant physical explanation derived from single-cell RNA-seq data. Most existing RNA velocity models aim to extract dynamics from the phase delay between unspliced and spliced mRNA for each individual gene. However, unspliced/spliced mRNA abundance may not provide sufficient signal for dynamic modeling, leading to poor fit in phase portraits.

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TFvelo: gene regulation inspired RNA velocity estimation - Nature Communications

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TFvelo: gene regulation inspired RNA velocity estimation - Nature Communications

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