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Eosinophils promote CD8+ T cell memory generation to potentiate anti-bacterial immunity - Signal Transduction and Targeted Therapy

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Eosinophils promote CD8+ T cell memory generation to potentiate anti-bacterial immunity - Signal Transduction and Targeted Therapy

Memory CD8+ T cell generation is crucial for pathogen elimination and effective vaccination against infection. The cellular and molecular circuitry that underlies the generation of memory CD8+ T cells remains elusive. Eosinophils can modulate inflammatory allergic responses and interact with lymphocytes to regulate their functions in immune defense. Here we report that eosinophils are required for the generation of memory CD8+ T cells by inhibiting CD8+ T cell apoptosis.

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Eosinophils promote CD8+ T cell memory generation to potentiate anti-bacterial immunity - Signal Transduction and Targeted Therapy

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Eosinophils promote CD8+ T cell memory generation to potentiate anti-bacterial immunity - Signal Transduction and Targeted Therapy

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Unlocking the Power of Knowledge
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Unlocking the Power of Knowledge
for Humanity's Progress