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Single-cell multi-omics analysis of lineage development and spatial organization in the human fetal cerebellum - Cell Discovery

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Single-cell multi-omics analysis of lineage development and spatial organization in the human fetal cerebellum - Cell Discovery

Human cerebellum encompasses numerous neurons, exhibiting a distinct developmental paradigm from cerebrum. Here we conducted scRNA-seq, scATAC-seq and spatial transcriptomic analyses of fetal samples from gestational week (GW) 13 to 18 to explore the emergence of cellular diversity and developmental programs in the developing human cerebellum. We identified transitory granule cell progenitors that are conserved across species.

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Single-cell multi-omics analysis of lineage development and spatial organization in the human fetal cerebellum - Cell Discovery

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Single-cell multi-omics analysis of lineage development and spatial organization in the human fetal cerebellum - Cell Discovery

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