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Regorafenib plus nivolumab in unresectable hepatocellular carcinoma: the phase 2 RENOBATE trial - Nature Medicine

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Regorafenib plus nivolumab in unresectable hepatocellular carcinoma: the phase 2 RENOBATE trial - Nature Medicine

Regorafenib has anti-tumor activity in patients with unresectable hepatocellular carcinoma (uHCC) with potential immunomodulatory effects, suggesting that its combination with immune checkpoint inhibitor may have clinically meaningful benefits in patients with uHCC. The multicenter, single-arm, phase 2 RENOBATE trial tested regorafenib–nivolumab as front-line treatment for uHCC.

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Regorafenib plus nivolumab in unresectable hepatocellular carcinoma: the phase 2 RENOBATE trial - Nature Medicine

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Regorafenib plus nivolumab in unresectable hepatocellular carcinoma: the phase 2 RENOBATE trial - Nature Medicine

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