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A rhesus macaque model of human norovirus infection - Nature Microbiology

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A rhesus macaque model of human norovirus infection - Nature Microbiology

Human norovirus infection is a major global health concern, but a suitable animal model is lacking. We have established repeated infection with human norovirus in rhesus macaques via oral challenge. Animals demonstrate virus shedding in the stool and subsequent serum antibody responses, and virus replication is detected in the small intestine.

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A rhesus macaque model of human norovirus infection - Nature Microbiology

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A rhesus macaque model of human norovirus infection - Nature Microbiology

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