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2 months ago

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Analytical characterization of full, intermediate, and empty AAV capsids - Gene Therapy

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Analytical characterization of full, intermediate, and empty AAV capsids - Gene Therapy

Manufacturing of recombinant adeno-associated virus (AAV) vectors produces three types of capsids: full, intermediate, and empty. While there are different opinions about the impact of intermediate and empty capsids on safety and efficacy of AAV products, they are generally considered impurities because they are not the intended fully intact vector product.

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Analytical characterization of full, intermediate, and empty AAV capsids - Gene Therapy

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Analytical characterization of full, intermediate, and empty AAV capsids - Gene Therapy

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