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IL-10 constrains sphingolipid metabolism to limit inflammation - Nature

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IL-10 constrains sphingolipid metabolism to limit inflammation - Nature

Interleukin-10 (IL-10) is a key anti-inflammatory cytokine that can limit immune cell activation and cytokine production in innate immune cell types1. Loss of IL-10 signalling results in life-threatening inflammatory bowel disease in humans and mice—however, the exact mechanism by which IL-10 signalling subdues inflammation remains unclear2–5. Here we

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IL-10 constrains sphingolipid metabolism to limit inflammation - Nature

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IL-10 constrains sphingolipid metabolism to limit inflammation - Nature

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