Article
Clearance of dead cells by efferocytosis promotes liver metastasis in pancreatic cancer - Nature Cancer
Rating:
0.0
Views:
25
Likes:
1
Library:
1
Pancreatic cancer liver metastases show high levels of immunosuppressive macrophages, which promote tumor growth. We found that blocking the efferocytosis pathway during early-stage metastasis in a mouse model inhibited the development of immunosuppressive activity in monocyte-derived macrophages, which restored T cell activation and reduced the metastatic tumor burden.
Rate This Post
Rate The Educational Value
Rate The Ease of Understanding and Presentation
Interesting or Boring? Rate the Entertainment Value