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Contractility drives the spatio-temporal coordination of morphogenesis and cell fate in hair follicles - Nature Cell Biology

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Contractility drives the spatio-temporal coordination of morphogenesis and cell fate in hair follicles - Nature Cell Biology

Contractile activity of both the epithelium and underlying mesenchyme are required for epithelial deformation and cell fate acquisition during early mouse hair follicle development. Subsequently, localized basement membrane remodelling facilitates the release of tension-generated pressure to promote cell divisions, tissue fluidification and downgrowth of the developing hair follicle.

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Contractility drives the spatio-temporal coordination of morphogenesis and cell fate in hair follicles - Nature Cell Biology

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Contractility drives the spatio-temporal coordination of morphogenesis and cell fate in hair follicles - Nature Cell Biology

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