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Impaired bone morphogenetic protein (BMP) signaling pathways disrupt decidualization in endometriosis - Communications Biology

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Impaired bone morphogenetic protein (BMP) signaling pathways disrupt decidualization in endometriosis - Communications Biology

Endometriosis is linked to increased infertility and pregnancy complications due to defective endometrial decidualization. We hypothesized that identification of altered signaling pathways during decidualization could identify the underlying cause of infertility and pregnancy complications. Our study reveals that transforming growth factor β (TGFβ) pathways are impaired in the endometrium of individuals with endometriosis, leading to defective decidualization.

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Impaired bone morphogenetic protein (BMP) signaling pathways disrupt decidualization in endometriosis - Communications Biology

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Impaired bone morphogenetic protein (BMP) signaling pathways disrupt decidualization in endometriosis - Communications Biology

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