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Synchronous force and Ca2+ measurements for repeated characterization of excitation-contraction coupling in human myocardium - Communications Biology

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Synchronous force and Ca2+ measurements for repeated characterization of excitation-contraction coupling in human myocardium - Communications Biology

Dysfunctional Ca2+ signaling affects the myocardial systole and diastole, may trigger arrhythmia and cause transcriptomic and proteomic modifications in heart failure. Thus, synchronous real-time measurement of Ca2+ and force is essential to investigate the relationship between contractility and Ca2+ signaling and the alteration of excitation-contraction coupling (ECC) in human failing myocardium.

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Synchronous force and Ca2+ measurements for repeated characterization of excitation-contraction coupling in human myocardium - Communications Biology

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Synchronous force and Ca2+ measurements for repeated characterization of excitation-contraction coupling in human myocardium - Communications Biology

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