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Intranasal vaccine for Lyme disease provides protection against tick transmitted Borrelia burgdorferi beyond one year - npj Vaccines

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Intranasal vaccine for Lyme disease provides protection against tick transmitted Borrelia burgdorferi beyond one year - npj Vaccines

Strategies for disease control are necessary to reduce incidence of Lyme Disease (LD) including development of safe vaccines for human use. Parainfluenza virus 5 (PIV5) vector has an excellent safety record in animals and PIV5-vectored vaccines are currently under clinical development. We constructed PIV5-vectored LD vaccine candidates expressing OspA from B. burgdorferi (OspAB31) and a chimeric protein containing sequences from B. burgdorferi and B. afzelii (OspABPBPk).

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Intranasal vaccine for Lyme disease provides protection against tick transmitted Borrelia burgdorferi beyond one year - npj Vaccines

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Intranasal vaccine for Lyme disease provides protection against tick transmitted Borrelia burgdorferi beyond one year - npj Vaccines

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