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VIBRANT: a phenotyping method for drug discovery using vibrational spectroscopy - Nature Methods

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VIBRANT: a phenotyping method for drug discovery using vibrational spectroscopy - Nature Methods

We developed a high-content profiling method named vibrational painting (VIBRANT) for single-cell drug response measurements, combining vibrational imaging, multiplexed vibrational probes and machine learning. VIBRANT showed high performance in predicting drug mechanisms of action, discovering novel compounds and assessing drug combinations, demonstrating great promise for phenotypic drug discovery.

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VIBRANT: a phenotyping method for drug discovery using vibrational spectroscopy - Nature Methods

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VIBRANT: a phenotyping method for drug discovery using vibrational spectroscopy - Nature Methods

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