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O-GlcNAc forces an α-synuclein amyloid strain with notably diminished seeding and pathology - Nature Chemical Biology
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Amyloid-forming proteins such α-synuclein and tau, which are implicated in Alzheimer's and Parkinson's disease, can form different fibril structures or strains with distinct toxic properties, seeding activities and pathology. Understanding the determinants contributing to the formation of different amyloid features could
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