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Protective efficacy of a Zika purified inactivated virus vaccine candidate during pregnancy in marmosets - npj Vaccines

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Protective efficacy of a Zika purified inactivated virus vaccine candidate during pregnancy in marmosets - npj Vaccines

Zika virus (ZIKV) infection during pregnancy poses significant threats to maternal and fetal health, leading to intrauterine fetal demise and severe developmental malformations that constitute congenital Zika syndrome (CZS). As such, the development of a safe and effective ZIKV vaccine is a critical public health priority. However, the safety and efficacy of such a vaccine during pregnancy remain uncertain. Historically, the conduct of clinical trials in pregnant women has been challenging.

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Protective efficacy of a Zika purified inactivated virus vaccine candidate during pregnancy in marmosets - npj Vaccines

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