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Maintenance of pig brain function under extracorporeal pulsatile circulatory control (EPCC) - Scientific Reports

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Maintenance of pig brain function under extracorporeal pulsatile circulatory control (EPCC) - Scientific Reports

Selective vascular access to the brain is desirable in metabolic tracer, pharmacological and other studies aimed to characterize neural properties in isolation from somatic influences from chest, abdomen or limbs. However, current methods for artificial control of cerebral circulation can abolish pulsatility-dependent vascular signaling or neural network phenomena such as the electrocorticogram even while preserving individual neuronal activity.

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Maintenance of pig brain function under extracorporeal pulsatile circulatory control (EPCC) - Scientific Reports

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Maintenance of pig brain function under extracorporeal pulsatile circulatory control (EPCC) - Scientific Reports

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