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Order and disorder in clathrin-mediated endocytosis - Nature Cell Biology

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Order and disorder in clathrin-mediated endocytosis - Nature Cell Biology

The generation of clathrin-coated vesicles during endocytosis requires the co-ordinated recruitment of dozens of proteins to the plasma membrane. We discovered that the plant TPLATE (or TSET) complex (TPC) undergoes biomolecular condensation through interactions with plasma membrane phospholipids and, via weak multivalent interactions, recruits clathrin and other endocytic proteins to facilitate the efficient progression of endocytosis.

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Order and disorder in clathrin-mediated endocytosis - Nature Cell Biology

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Order and disorder in clathrin-mediated endocytosis - Nature Cell Biology

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