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Effects of cannabidiol in post-stroke mood disorders in neonatal rats - Pediatric Research

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Effects of cannabidiol in post-stroke mood disorders in neonatal rats - Pediatric Research

Neonatal rats can manifest post-stroke mood disorders (PSMD) following middle cerebral artery occlusion (MCAO). We investigated whether cannabidiol (CBD) neuroprotection, previously demonstrated in neonatal rats after MCAO, includes prevention of PSMD development. Seven-day-old Wistar rats (P7) underwent MCAO and received either vehicle or 5 mg/kg CBD treatment. Brain damage was quantified by MRI, and neurobehavioral and histological (TUNEL) studies were performed at P14 and P37.

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Effects of cannabidiol in post-stroke mood disorders in neonatal rats - Pediatric Research

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Effects of cannabidiol in post-stroke mood disorders in neonatal rats - Pediatric Research

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