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CD97 inhibits osteoclast differentiation via Rap1a/ERK pathway under compression - International Journal of Oral Science

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CD97 inhibits osteoclast differentiation via Rap1a/ERK pathway under compression - International Journal of Oral Science

Acceleration of tooth movement during orthodontic treatment is challenging, with osteoclast-mediated bone resorption on the compressive side being the rate-limiting step. Recent studies have demonstrated that mechanoreceptors on the surface of monocytes/macrophages, especially adhesion G protein-coupled receptors (aGPCRs), play important roles in force sensing. However, its role in the regulation of osteoclast differentiation remains unclear.

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CD97 inhibits osteoclast differentiation via Rap1a/ERK pathway under compression - International Journal of Oral Science

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CD97 inhibits osteoclast differentiation via Rap1a/ERK pathway under compression - International Journal of Oral Science

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