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Biomolecular condensation orchestrates clathrin-mediated endocytosis in plants - Nature Cell Biology

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Biomolecular condensation orchestrates clathrin-mediated endocytosis in plants - Nature Cell Biology

Clathrin-mediated endocytosis is an essential cellular internalization pathway involving the dynamic assembly of clathrin and accessory proteins to form membrane-bound vesicles. The evolutionarily ancient TSET–TPLATE complex (TPC) plays an essential, but ill-defined role in endocytosis in plants. Here we show that two highly disordered TPC subunits, AtEH1 and AtEH2, function as scaffolds to drive biomolecular condensation of the complex.

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Biomolecular condensation orchestrates clathrin-mediated endocytosis in plants - Nature Cell Biology

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Biomolecular condensation orchestrates clathrin-mediated endocytosis in plants - Nature Cell Biology

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