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Single nucleus transcriptomics of ventral midbrain identifies glial activation associated with chronic opioid use disorder - Nature Communications

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Single nucleus transcriptomics of ventral midbrain identifies glial activation associated with chronic opioid use disorder - Nature Communications

Dynamic interactions of neurons and glia in the ventral midbrain mediate reward and addiction behavior. We studied gene expression in 212,713 ventral midbrain single nuclei from 95 individuals with history of opioid misuse, and individuals without drug exposure.

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Single nucleus transcriptomics of ventral midbrain identifies glial activation associated with chronic opioid use disorder - Nature Communications

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Single nucleus transcriptomics of ventral midbrain identifies glial activation associated with chronic opioid use disorder - Nature Communications

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