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Spatial correspondence among regional gene expressions and gray matter volume loss in multiple sclerosis - Molecular Psychiatry

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Spatial correspondence among regional gene expressions and gray matter volume loss in multiple sclerosis - Molecular Psychiatry

In multiple sclerosis (MS), a non-random and clinically relevant pattern of gray matter (GM) volume loss has been described. Whether differences in regional gene expression might underlay distinctive pathological processes contributing to this regional variability has not been explored yet. Two hundred eighty-six MS patients and 172 healthy controls (HC) underwent a brain 3T MRI, a complete neurological evaluation and a neuropsychological assessment.

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Spatial correspondence among regional gene expressions and gray matter volume loss in multiple sclerosis - Molecular Psychiatry

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Spatial correspondence among regional gene expressions and gray matter volume loss in multiple sclerosis - Molecular Psychiatry

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