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3 months ago

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Shigella virulence protein VirG is a broadly protective antigen and vaccine candidate - npj Vaccines

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Shigella virulence protein VirG is a broadly protective antigen and vaccine candidate - npj Vaccines

Diarrhea caused by Shigella has been associated with high morbidity and mortality in young children worldwide. There are no licensed vaccines, and those clinically advanced have restricted coverage as they elicit serotype-specific immunity while disease is caused by multiple circulating serotypes. Our group had previously reported a close association between serum antibodies to the Shigella virulence factor VirG (or IcsA) and clinical protection in infected individuals.

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Shigella virulence protein VirG is a broadly protective antigen and vaccine candidate - npj Vaccines

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