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Emergence, transmission dynamics and mechanisms of artemisinin partial resistance in malaria parasites in Africa - Nature Reviews Microbiology

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Emergence, transmission dynamics and mechanisms of artemisinin partial resistance in malaria parasites in Africa - Nature Reviews Microbiology

Malaria, mostly due to Plasmodium falciparum infection in Africa, remains one of the most important infectious diseases in the world. Standard treatment for uncomplicated P. falciparum malaria is artemisinin-based combination therapy (ACT), which includes a rapid-acting artemisinin derivative plus a longer-acting partner drug, and standard therapy for severe P. falciparum malaria is intravenous artesunate.

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Emergence, transmission dynamics and mechanisms of artemisinin partial resistance in malaria parasites in Africa - Nature Reviews Microbiology

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Emergence, transmission dynamics and mechanisms of artemisinin partial resistance in malaria parasites in Africa - Nature Reviews Microbiology

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