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Multi-modal cryo-EM reveals trimers of protein A10 to form the palisade layer in poxvirus cores - Nature Structural & Molecular Biology

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Multi-modal cryo-EM reveals trimers of protein A10 to form the palisade layer in poxvirus cores - Nature Structural & Molecular Biology

Poxviruses are among the largest double-stranded DNA viruses, with members such as variola virus, monkeypox virus and the vaccination strain vaccinia virus (VACV). Knowledge about the structural proteins that form the viral core has remained sparse. While major core proteins have been annotated via indirect experimental evidence, their structures have remained elusive and they could not be assigned to individual core features.

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Multi-modal cryo-EM reveals trimers of protein A10 to form the palisade layer in poxvirus cores - Nature Structural & Molecular Biology

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Multi-modal cryo-EM reveals trimers of protein A10 to form the palisade layer in poxvirus cores - Nature Structural & Molecular Biology

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