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Role of UPF1 in lncRNA-HEIH regulation for hepatocellular carcinoma therapy - Experimental & Molecular Medicine

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Role of UPF1 in lncRNA-HEIH regulation for hepatocellular carcinoma therapy - Experimental & Molecular Medicine

UPF1, a novel posttranscriptional regulator, regulates the abundance of transcripts, including long noncoding RNAs (lncRNAs), and thus plays an important role in cell homeostasis. In this study, we revealed that UPF1 regulates the abundance of hepatocellular carcinoma upregulated EZH2-associated lncRNA (lncRNA-HEIH) by binding the CG-rich motif, thereby regulating hepatocellular carcinoma (HCC) tumorigenesis.

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Role of UPF1 in lncRNA-HEIH regulation for hepatocellular carcinoma therapy - Experimental & Molecular Medicine

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Role of UPF1 in lncRNA-HEIH regulation for hepatocellular carcinoma therapy - Experimental & Molecular Medicine

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