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METTL3 promotes colorectal cancer progression through activating JAK1/STAT3 signaling pathway - Cell Death & Disease

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METTL3 promotes colorectal cancer progression through activating JAK1/STAT3 signaling pathway - Cell Death & Disease

The role of METTL3-mediated N6-methyladenosine (m6A) modification has been elucidated in several cancers, but the concrete mechanism underlying its function in colorectal cancer is still obscure. Here, we revealed that upregulated methyltransferase-like 3 (METTL3) in colorectal cancer exerted both methyltransferase activity-dependent and -independent functions in gene regulation.

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METTL3 promotes colorectal cancer progression through activating JAK1/STAT3 signaling pathway - Cell Death & Disease

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METTL3 promotes colorectal cancer progression through activating JAK1/STAT3 signaling pathway - Cell Death & Disease

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Unlocking the Power of Knowledge
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